1187 studies on GLP-1 agonist class curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
This landmark study provides strong evidence that current recommendations for discontinuing GLP-1/GIP agonists before upper endoscopy may be overly cautious. The findings suggest that patients can safely continue thei…
This research provides crucial evidence that GLP-1 medicines offer a superior weight loss profile by effectively reducing fat mass while preserving vital muscle mass and function. This finding is particularly signific…
This exploratory analysis suggests liraglutide could offer a multi-faceted therapeutic approach for individuals grappling with the complex and often debilitating combination of obesity, OSA, and COPD. By effectively p…
This comprehensive meta-analysis provides compelling and robust evidence that GLP-1 Receptor Agonists offer substantial cardiovascular and renal protection for patients with Type 2 Diabetes, critically, irrespective o…
This review underscores the critical role of adjunct therapies in optimizing metabolic health beyond insulin in Type 1 Diabetes. The findings suggest that these medications could significantly improve patient outcomes…
This umbrella review significantly expands our understanding of the pleiotropic effects of GLP-1 RAs, suggesting their therapeutic potential extends far beyond their current indications. These findings provide strong …
This research highlights a critical aspect of GLP-1 physiology: its anorectic effects are not uniform but are significantly influenced by dietary macronutrient composition. This finding could have profound implication…
This research reveals a novel mechanism by which lorcaserin contributes to appetite suppression and, more importantly, identifies a powerful synergistic interaction with GLP-1 receptor agonists. This finding suggests …
This comprehensive review highlighted the diverse and innovative approaches being explored to combat obesity in the early 2000s. The identification of multiple drug classes, from central nervous system modulators to p…
This comprehensive meta-analysis strongly reinforces Liraglutide's established role as an effective and safe treatment for T2DM, offering significant benefits beyond glycemic control, including clinically meaningful w…
This study offers crucial insights into the sociocultural dimensions of semaglutide use, extending beyond its pharmacological effects. Understanding the social stigma and public perceptions associated with medication-…
This research highlights a crucial, often overlooked, aesthetic side effect of rapid weight loss induced by GLP-1 RAs, which can significantly impact patient satisfaction and body image. Understanding this phenomenon …
This real-world study reinforces the significant cardiovascular protective effects of GLP-1 Receptor Agonists and SGLT-2 Inhibitors in a diverse primary care population with Type 2 Diabetes. The findings provide cruci…
This study provides crucial real-world validation of semaglutide's effectiveness in a large Chinese population, reinforcing its role as a powerful therapeutic option for Type 2 Diabetes. The significant improvements i…
This meta-analysis provides critical evidence that while semaglutide is highly effective for many, a substantial subset of patients experiences suboptimal weight or glycemic improvements or discontinues therapy. This …
This review is critical for advancing the understanding and treatment of MASH, a disease with significant unmet medical needs. It provides a roadmap for developing more effective, patient-specific therapies, moving be…
This large-scale, real-world data provides crucial insights into the safety profile of GLP-1 receptor agonists when exposure occurs around conception. The reassurance regarding major congenital malformations is partic…
This comprehensive review provides crucial insights for clinicians prescribing GLP-1 receptor agonists, emphasizing the importance of considering potential ocular risks alongside the well-known benefits. The findings …
This study provides compelling evidence that GLP-1 RAs offer significant benefits beyond metabolic control, extending to crucial aspects of mental health and cognitive function. These findings suggest a potential for …
These pivotal Phase 3 trials definitively demonstrate that oral semaglutide 14 mg, at the tested dose and duration, is not an effective treatment for slowing cognitive decline in early symptomatic Alzheimer's disease.…
This research highlights the critical importance of considering sex as a biological variable in metabolic research and clinical practice. The observed protection in females against semaglutide-induced muscle loss coul…
This comprehensive update highlights that resmetirom, a selective thyroid hormone receptor-beta (THR-β) agonist, represents a groundbreaking advancement in the treatment of MASH. Its recent FDA approval as the first d…
The analysis revealed that a significant portion of media reports, approximately 45%, contained inaccuracies or presented information without adequate scientific context regarding the link between Semaglutide and NAIO…
This newly developed ECLIA offers a highly sensitive, specific, and robust platform for measuring semaglutide levels in human serum, significantly advancing analytical capabilities. Such a precise method is invaluable…
This study highlights the synergistic benefits of combining oral semaglutide with levothyroxine for patients suffering from both Type 2 Diabetes and hypothyroidism. The significant improvements in glycemic control, we…
This real-world evidence strongly supports the effectiveness and safety of oral semaglutide in a diverse Asian population, mirroring results from controlled clinical trials. The convenience of an oral formulation can …
This study highlights a significant barrier to effective patient education for widely used medications like semaglutide. Most online semaglutide patient education is inaccessible to the average person, potentially hin…
This study provides compelling evidence that oral semaglutide not only reduces major adverse cardiovascular events (as demonstrated in the primary SOUL trial) but also profoundly improves a wide array of individual ca…
This study provides compelling evidence that GLP-1 receptor agonists offer significant cardioprotective benefits beyond their established roles in glycemic control and weight management. The robust reduction in heart …
These findings provide critical, real-world insights into the sexual safety profiles of widely used antidiabetic medications, which are often missed in controlled clinical trials. This information is vital for healthc…
This review underscores the critical importance of early identification and aggressive management of MASLD in obese youth to mitigate the escalating risk of type 2 diabetes. Recognizing MASLD not just as a liver condi…
This study provides crucial real-world evidence supporting the safe and effective use of GLP-1 RAs in a vulnerable population previously lacking dedicated research. The observed improvements in glycemic control, weigh…
This systematic review underscores the urgent need for more comprehensive human data to guide clinical practice. Given the rising prevalence of obesity and type 2 diabetes in women of reproductive age, understanding t…
This study provides crucial evidence supporting the safety and continued efficacy of Semaglutide in a highly vulnerable patient population. For patients with type 2 diabetes and end-stage renal disease (ESRD) on dialy…
This case report is crucial for increasing clinical awareness regarding the potential for severe altered mental status as a manifestation of amantadine withdrawal. It underscores the importance of a thorough medicatio…
This comprehensive benchmarking study provides invaluable guidance for pharmaceutical scientists and quality control laboratories in selecting the most efficient and effective SEC columns. By optimizing SEC methods, r…
This study provides compelling evidence that semaglutide 1.7 mg is a highly effective and generally well-tolerated treatment option for adolescent obesity, a condition with limited pharmacological interventions. Given…
This study highlights a critical emerging trend in plastic surgery, demonstrating how advancements in pharmacotherapy for weight loss directly influence the demand for body contouring procedures. Understanding this sh…
This comprehensive meta-analysis provides robust evidence supporting the cardioprotective effects and favorable safety profile of GLP-1 Receptor Agonists in elderly patients with Type 2 Diabetes. Given the high burden…