48 studies on Mitochondrial peptide class curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
Identifying an early and reliable biomarker for AKI after heart transplantation is critically important, as it could enable clinicians to intervene sooner, potentially preventing severe kidney damage and improving pat…
Understanding the precise role of Humanin in the context of cardiac surgery outcomes could significantly advance patient care and risk management. If specific Humanin levels are found to correlate with, or predict, th…
This research is significant because it identifies Quercetin, a natural flavonoid, as a potential therapeutic agent for renal ischemia-reperfusion injury, a condition with limited current treatment options. The findin…
This review is crucial because it highlights the urgent need for effective treatments for dry AMD, a condition affecting millions globally with no current cure. The identification of innovative technologies like gene …
This comprehensive review underscores the critical role of mitochondria as a promising therapeutic target for preventing and treating acute kidney injury (AKI) caused by ischemia-reperfusion injury (IRI). By elucidati…
SS-31 represents a highly promising therapeutic strategy for a wide range of conditions characterized by mitochondrial dysfunction, offering a direct and targeted approach to cellular protection. Its unique ability to…
Understanding the role of exercise in post-diagnosis breast cancer care is crucial for improving patient outcomes and quality of life. If this pilot study demonstrates positive changes in body composition and identifi…
The ability to accurately predict cardiovascular mortality in Type 2 Diabetes Mellitus patients with Coronary Artery Disease is paramount for enhancing patient care and improving long-term outcomes. Positive findings …
MOTS-c is a novel mitochondrial-derived peptide with potential roles in metabolic regulation, including glucose homeostasis. If this Phase 2a study demonstrates significant improvements in insulin sensitivity and a fa…
This review provides novel insights into the critical role of mitochondrial calcium dysregulation in heart failure, underscoring its potential as a therapeutic target. The discussion of mCa2+ uniporter (MCU) inhibitor…
These findings underscore SS-31's significant potential as a novel therapeutic agent for managing and treating inflammatory liver conditions. By elucidating its mechanism through ATG5-dependent autophagy, this researc…
This review underscores the pivotal role of mitochondria in determining the trajectory of recovery and long-term neurological health after TBI. By identifying mitochondrial dysfunction as a key pathological mechanism,…
This research fundamentally shifts our understanding of how telomere length is established and inherited, demonstrating its modifiability during the earliest stages of embryonic development. The ability to intervene w…
This research provides compelling evidence that mitochondrial dysfunction is a primary driver of age-related aortic degeneration. The successful intervention with elamipretide highlights its potential as a therapeutic…
This research provides strong evidence that mitochondrial dysfunction is a primary driver of aortic aging, offering a novel understanding of age-related cardiovascular decline. The successful restoration of mitochondr…
This research provides a novel mechanistic understanding of how endurance training improves skeletal muscle mitochondrial function, highlighting MOTS-c as a key player. The findings suggest that circulating MOTS-c lev…
These findings are highly significant as they identify MOTS-c as a critical regulator of pancreatic islet cell senescence, a process implicated in both type 1 and type 2 diabetes. The ability of MOTS-c to reduce senes…
This research highlights MOTS-c as a promising therapeutic candidate for osteoarthritis, offering a novel approach by simultaneously targeting mitochondrial health, reducing inflammatory cell death, and activating pro…
This review highlights a significant untapped area of research with profound implications for understanding and treating lung diseases. Given the established roles of MDPs in other complex diseases, their investigatio…
This detailed chemical profile is crucial for the unambiguous identification and characterization of MOTS-c in research and development. Accurate chemical identification is the bedrock for all subsequent experimental …
Friedreich Ataxia (FRDA) currently lacks effective treatments for vision loss, a symptom that significantly impacts patients' independence and quality of life. Positive results from this pilot study could validate Ela…
This comprehensive screening program holds immense potential to revolutionize early intervention strategies for newborn hearing loss. By identifying genetic causes early, clinicians can offer more personalized prognos…