37 studies on Growth hormone class curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
A successful Phase 3 trial of Saizen® for Idiopathic Short Stature (ISS) could significantly impact pediatric endocrinology by providing robust evidence for a standardized and effective treatment protocol. For clinici…
This study provides promising early evidence that recombinant human growth hormone (rhGH) could be a safe and effective therapeutic option for adolescents grappling with NAFLD. The observed improvements in liver fat, …
If the study demonstrates positive results, it could establish recombinant human growth hormone (rhGH) as a critical and effective treatment for short stature in children with chronic kidney disease prior to transplan…
This study is crucial for strengthening the global fight against doping, particularly concerning growth hormone abuse. By successfully generating standardized, positive control samples, it provides anti-doping laborat…
The development of a sustained-release human growth hormone (SR-hGH) formulation could significantly improve treatment adherence and quality of life for children with Idiopathic Short Stature (ISS) by reducing injecti…
The successful completion of this Phase 1 trial is a crucial step towards providing a more convenient treatment option for children with Growth Hormone Deficiency. A long-acting growth hormone like somapacitan could s…
This study successfully focused on the development, implementation, and initial validation of the MAGHD App/MAGHD Framework as a novel self-assessment system for Adult Growth Hormone Deficiency (AGHD) management. The …
The termination of this trial highlights the significant challenges in developing and testing combination therapies for complex conditions like IGF-1 deficiency and short stature. While this specific study did not yie…
This study is significant because it investigated the impact of very early initiation of growth hormone therapy in Turner Syndrome, a critical period for growth and development. The findings, once fully published, cou…
This synthesis of evidence underscores the critical role of growth hormone (GH) in driving breast cancer progression, metastasis, and angiogenesis, moving beyond the traditional focus on steroid hormones. Understandin…
The successful identification of AOD9604 in seized illicit preparations highlights the growing challenge posed by counterfeit and unregulated peptide drugs on the black market. This analytical capability is vital for …
This compelling case report highlights the significant potential of the GHRP-2 test as a highly sensitive and specific diagnostic marker for Cushing's disease, particularly in cases involving ACTH-producing pituitary …
**Any consumer purchasing this supplement was unknowingly ingesting a WADA-prohibited peptide capable of stimulating the hGH/IGF-1 axis**, with no dosing guidance, safety oversight, or disclosure. For athletes, a posi…
**GHRP-2 is an active masking agent for rhGH doping** that can depress a positive isoform test result by more than half — anyone combining GHRP-2 with rhGH for performance enhancement should understand this interactio…
This study demonstrates a critical nuance in GH secretagogue therapy: simply stimulating a transient pulse of endogenous GH may not be sufficient to drive meaningful clinical outcomes like growth in GHD patients. For …
For athletes and regulatory bodies, this research provides a pathway to more effective and reliable anti-doping controls for hGH. The identification of `RAB31` and `FN1` as robust biomarkers could lead to new testing …
The identification of this novel GHRP-2 analogue highlights a concerning trend in illicit drug manufacturing: the deliberate modification of known prohibited substances to create 'designer' peptides that can evade det…
This automated system significantly enhances the capabilities of anti-doping programs. By enabling reliable, quantitative analysis from Dried Blood Spot samples, it makes collection less invasive and sample handling m…
This report highlights that the illicit drug market in Europe extends beyond commonly recognized categories like ED drugs. For users of peptides and other biopharmaceuticals, this is a stark reminder of the risks asso…
The widespread availability of falsified peptides like Melanotan II on the black market poses a direct and severe risk to end-users. Consumers have no assurance of what they are injecting, risking exposure to incorrec…
This comprehensive review underscores the broad therapeutic potential of GHS across multiple organ systems and conditions. The observed benefits, from cardioprotection and growth promotion to metabolic improvements an…
The discovery of capromorelin represents a significant advancement in the development of orally active Growth Hormone Secretagogues (GHSs). Its excellent bioavailability and oral activity directly address a major hurd…
This review underscores the critical need for more robust, evidence-based interventions to address somatopause and its associated age-related conditions. The findings highlight that current GH therapy, despite its pop…
**AOD9604's lipolytic mechanism is indirect**: it drives `beta(3)-AR` gene expression upward rather than binding the receptor itself, meaning protocols relying on stacking it with `beta3-AR` agonists (e.g., ephedrine-…
**AOD-9604's inclusion in a formal clinical trials gateway** confirms it held active investigational status at the time of publication, meaning regulatory and sponsor-level interest was sufficient to warrant indexed t…
**Inclusion in a formal clinical trials gateway signals that AOD-9604 had reached a stage of development warranting systematic tracking in the peer-reviewed clinical literature.** For clinicians and researchers, this …
This comprehensive review highlighted the diverse and innovative approaches being explored to combat obesity in the early 2000s. The identification of multiple drug classes, from central nervous system modulators to p…
This research provides a critical advancement for anti-doping efforts, offering a highly sensitive and reliable method for detecting AOD9604 abuse. The identification of a significantly more stable metabolite, CRSVEGS…
This research reveals the specific chemical modifications being made to performance-enhancing drugs on the black market, providing critical intelligence for anti-doping agencies. The discovery of a 192-amino-acid GH v…