40 studies on Growth hormone class curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
A successful Phase 3 trial of Saizen® for Idiopathic Short Stature (ISS) could significantly impact pediatric endocrinology by providing robust evidence for a standardized and effective treatment protocol. For clinici…
This study provides promising early evidence that recombinant human growth hormone (rhGH) could be a safe and effective therapeutic option for adolescents grappling with NAFLD. The observed improvements in liver fat, …
If the study demonstrates positive results, it could establish recombinant human growth hormone (rhGH) as a critical and effective treatment for short stature in children with chronic kidney disease prior to transplan…
This study is crucial for strengthening the global fight against doping, particularly concerning growth hormone abuse. By successfully generating standardized, positive control samples, it provides anti-doping laborat…
The development of a sustained-release human growth hormone (SR-hGH) formulation could significantly improve treatment adherence and quality of life for children with Idiopathic Short Stature (ISS) by reducing injecti…
The successful completion of this Phase 1 trial is a crucial step towards providing a more convenient treatment option for children with Growth Hormone Deficiency. A long-acting growth hormone like somapacitan could s…
This case critically emphasizes the importance for healthcare providers to recognize and meticulously evaluate false-positive beta-hCG results in patients diagnosed with end-stage renal disease. Misinterpreting these …
This study successfully focused on the development, implementation, and initial validation of the MAGHD App/MAGHD Framework as a novel self-assessment system for Adult Growth Hormone Deficiency (AGHD) management. The …
The termination of this trial highlights the significant challenges in developing and testing combination therapies for complex conditions like IGF-1 deficiency and short stature. While this specific study did not yie…
This study is significant because it investigated the impact of very early initiation of growth hormone therapy in Turner Syndrome, a critical period for growth and development. The findings, once fully published, cou…
This study represents a significant advancement in the management of pediatric growth hormone deficiency, offering a more convenient treatment regimen that could substantially improve patient adherence and quality of …
This synthesis of evidence underscores the critical role of growth hormone (GH) in driving breast cancer progression, metastasis, and angiogenesis, moving beyond the traditional focus on steroid hormones. Understandin…
This research introduces a groundbreaking method for recombinant protein production, offering a simpler, more cost-effective, and highly efficient pathway to obtain functional proteins. By enabling direct recovery of …
This finding is critically important for the integrity of anti-doping efforts worldwide. It confirms that the WADA hGH isoform immunoassay remains a reliable tool for detecting human growth hormone abuse, even with th…
The successful identification of AOD9604 in seized illicit preparations highlights the growing challenge posed by counterfeit and unregulated peptide drugs on the black market. This analytical capability is vital for …
The review highlights that diagnosing aGHD in brain-injured patients can be particularly challenging due to overlapping symptoms with post-concussion syndrome and other neurological sequelae. However, it underscores t…
This compelling case report highlights the significant potential of the GHRP-2 test as a highly sensitive and specific diagnostic marker for Cushing's disease, particularly in cases involving ACTH-producing pituitary …
This research is significant because it identifies an alternative pathway for stimulating growth hormone release in a severe model of GH deficiency. The finding that GHRP-2 can bypass the primary genetic defect in Ghr…
The findings from this research are highly significant as this new panel of genetic and protein biomarkers offers a substantially more robust and prolonged detection window for identifying growth hormone abuse. This e…
The identification of this novel GHRP-2 analogue highlights a concerning trend in illicit drug manufacturing: the deliberate modification of known prohibited substances to create 'designer' peptides that can evade det…
This comprehensive review underscores the broad therapeutic potential of GHS across multiple organ systems and conditions. The observed benefits, from cardioprotection and growth promotion to metabolic improvements an…
The discovery of capromorelin represents a significant advancement in the development of orally active Growth Hormone Secretagogues (GHSs). Its excellent bioavailability and oral activity directly address a major hurd…
This research strongly suggests that targeting the GH/IGF-1 axis could be a powerful strategy to combat age-related cardiovascular decline and improve vascular health. By restoring endothelial progenitor cell (EPC) fu…
This review underscores the critical need for more robust, evidence-based interventions to address somatopause and its associated age-related conditions. The findings highlight that current GH therapy, despite its pop…
This study provides compelling evidence that AOD9604, a specific fragment of human GH, can effectively reduce obesity and improve lipid metabolism without the adverse effects on glucose homeostasis typically associate…
This comprehensive review highlighted the diverse and innovative approaches being explored to combat obesity in the early 2000s. The identification of multiple drug classes, from central nervous system modulators to p…
This research provides a critical advancement for anti-doping efforts, offering a highly sensitive and reliable method for detecting AOD9604 abuse. The identification of a significantly more stable metabolite, CRSVEGS…
This research highlights Ipamorelin's potential as a potent and selective growth hormone secretagogue capable of directly stimulating bone growth. Its efficacy, comparable to recombinant human GH in this model, sugges…
This study unequivocally highlights the severe public health risks associated with the use of unregulated black market growth-promoting products. Consumers are frequently exposed to mislabeled, contaminated, or entire…
This research is profoundly significant as it provides a robust proof-of-concept for creating long-acting peptide therapeutics through the innovative strategy of albumin bioconjugation. The identification of CJC-1295 …
The ability of Sermorelin to stimulate the body's natural GH production offers a significant advantage over direct GH replacement, potentially reducing side effects and maintaining physiological feedback loops. This a…
This study provides compelling evidence that Epitalon can positively influence key biological pathways associated with aging, specifically by enhancing telomerase activity and preserving telomere length. The observed …