111 studies on Antimicrobial peptide class curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
This research highlights LL-37 as a promising candidate for a new class of antimalarial drugs, offering a novel mechanism of action that could circumvent existing drug resistance. The peptide's ability to selectively …
This research provides critical insights into the complex interplay between host defense peptides and bacterial components within the oral biofilm, highlighting a previously unrecognized mechanism by which LL-37 might…
This study provides compelling evidence that Vicenin-2, a natural flavonoid, can effectively alleviate rosacea-like inflammation by specifically targeting the IL-17RA signaling pathway. This novel mechanism of action …
This research provides a fundamental understanding of how protamine triggers adverse reactions by directly activating mast cells via MRGPRX2. The finding that heparin can effectively block this activation is particula…
These findings fundamentally advance our understanding of how antimicrobial peptides interact, highlighting that peptide aggregation is a critical determinant of AMP structure-function relationships. This mechanistic …
These findings highlight LL-37's potential as a novel therapeutic agent to combat cancer metastasis, a major cause of cancer-related mortality. By controlling cancer cell migration, LL-37 could offer a new strategy to…
This feasibility study is a crucial foundational step towards understanding if vitamin D supplementation can significantly improve outcomes for patients undergoing non-surgical periodontal treatment. If confirmed in l…
This research highlights a novel mechanism of synergistic antimicrobial action driven by peptide aggregation dynamics. Understanding how LL-37 and HNP1 cooperatively assemble to enhance bacterial killing provides a cr…
This mechanistic framework offers a profoundly valuable conceptual model, providing a clearer lens through which to understand the complex and multifactorial etiology of Inflammatory Bowel Disease. It serves as a crit…