28 studies on Kisspeptin receptor agonist class curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
This study provides critical insights into the postpubertal role of MKRN3, suggesting it may act as a brake on reproductive function even after maturity, potentially contributing to reproductive disorders. Understandi…
This research highlights Kisspeptin's potential as a therapeutic agent for mitigating the adverse effects of maternal hypothyroidism on pregnancy outcomes. The restoration of placental mTOR signaling and glucose homeo…
This research highlights the central role of impaired decidualization in the pathogenesis and progression of CSP, suggesting it's not just about implantation location but also the uterine environment's receptivity. Un…
This research highlights Kisspeptin-10 as a promising novel therapeutic agent for combating the neurological complications of HIV-1 infection, particularly HIV-associated neurocognitive disorders (HAND). By specifical…
This study strongly suggests that Kisspeptin could serve as a novel, non-invasive biomarker for diagnosing male infertility, particularly when measured in seminal plasma due to its stronger correlation. Developing a s…
This groundbreaking research identifies Kisspeptin-10 as a highly promising therapeutic agent for mitigating post-stroke brain injury by directly targeting and preserving the blood-brain barrier. By significantly upre…
This research provides crucial insights into the physiological fluctuations of kisspeptin and irisin during the normal menstrual cycle, highlighting their potential roles beyond their previously established functions.…
This study provides compelling evidence that kisspeptin-10 acts as a pleiotropic agent, meaning it exerts multiple beneficial effects, against triple-negative breast cancer. Its unique ability to simultaneously suppre…
This study provides crucial human data, indicating that an acute intravenous bolus of kisspeptin 112-121 at the tested dose is not effective as a provocative diagnostic test for AVP-D. This finding refines our underst…
This study highlights Kisspeptin-10 as a promising novel therapeutic candidate for the management of obesity and type 2 diabetes. Its multifaceted action, involving both the enhancement of beneficial gut hormones and …
This study highlights Kisspeptin-10 as a promising therapeutic candidate for glioblastoma by simultaneously targeting EMT and inducing apoptosis, two critical pathways in cancer progression. Its ability to disrupt mul…
This research positions kisspeptins as a highly promising new therapeutic candidate for the treatment of endometriosis. By simultaneously targeting both the invasion of endometrial cells and the angiogenesis that fuel…
This research highlights Kisspeptin's significant potential as a therapeutic agent for managing pregnancy complications arising from maternal hypothyroidism. By restoring critical placental signaling pathways like mTO…
This meta-analysis provides robust evidence that serum kisspeptin levels are consistently lower in women with PCOS, suggesting its potential as a novel biomarker for the condition. The findings deepen our understandin…
This research highlights Kisspeptin-10's significant potential as a therapeutic agent for addressing infertility and various reproductive disorders. By elucidating the involvement of the PI3K/AKT/ERK signaling pathway…
This research provides critical insights into the neuroendocrine mechanisms underlying delayed puberty, particularly highlighting the imbalance within the KNDy system. Understanding these specific peptide dysregulatio…
This research highlights the Kisspeptin/GPR54 axis as a novel and promising therapeutic target for PAH, a disease with limited effective treatments. By restoring mitochondrial function and normalizing mitophagy in PAS…
Understanding how the HPG axis responds to stimulation like Kisspeptin-10 across different age groups is crucial for addressing age-related reproductive health issues. This research provides foundational insights into…
While this specific study did not yield results, the initial intent highlights the potential scientific interest in Kisspeptin-10 as a modulator of insulin secretion. If future research successfully demonstrates a rol…
Understanding the interplay between reproductive hormones like kisspeptin and metabolic processes could open new avenues for treating metabolic diseases. If kisspeptin were found to positively influence insulin secret…
This study provides compelling evidence that exogenous Kisspeptin-10 can effectively restore reproductive hormone balance and improve fertility in models of hypogonadotropic hypogonadism. The significant increases in …