2 studies on Sirt1 mechanism curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
This study identifies ghrelin as a potent neuroprotective agent in a preclinical model of neonatal brain injury, operating through a clearly defined signaling pathway that combats oxidative stress and cell death. For …
This research provides a strong preclinical rationale for using acylated ghrelin as a potential adjunctive therapy to mitigate the kidney damage caused by doxorubicin chemotherapy. For individuals undergoing DOX treat…