Orexin receptor antagonist

1 study on Orexin receptor antagonist mechanism curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.

2026-04-03 PubMed · preclinical animal · n preclinical

Centrally-administered ghrelin blocks LPS-induced colonic hyperpermeability in rats via the vagus nerve

This research reveals a specific brain-gut axis mechanism where central ghrelin signaling robustly protects the intestinal barrier against inflammatory damage. For individuals exploring peptides, this highlights a pot…

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