Ghsr 1α agonist

1 study on Ghsr 1α agonist mechanism curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.

2026-04-03 PubMed · preclinical animal · n preclinical

Ghrelin attenuates neuronal apoptosis and oxidative stress in a rat model of neonatal HIE via the GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 pathway.

This study identifies ghrelin as a potent neuroprotective agent in a preclinical model of neonatal brain injury, operating through a clearly defined signaling pathway that combats oxidative stress and cell death. For …

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