2 studies on Akt pathway mechanism curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
**GHRH antagonists like JMR-132 may represent a mechanistically distinct antiproliferative strategy** for ovarian cancers expressing SV1 of the GHRH receptor, targeting the `EGFR-Akt` axis without being a direct EGFR …
This research reframes Melanotan-II from a controversial tanning agent to a potential topical therapeutic for **melanoma**. For peptide users, this suggests a previously unappreciated anti-cancer mechanism, challengin…