Semaglutide drives weight loss by engaging Gs/Gq pathways and cAMP in hindbrain GLP1R neurons.
Semaglutide drives weight loss through cAMP-dependent mechanisms in GLP1R-expressing hindbrain neurons.
Abstract
Semaglutide drives weight loss by activating Gs- and Gq-dependent signaling in hindbrain GLP1R neurons, with cAMP increases via Gs being critical. Disrupting these pathways abolishes semaglutide's weight loss.
TitrateLab articles covering Semaglutide
Written by TitrateLab, separately from the study summarized above.
