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ipamorelin ghrelin mimetic other 2026-04-03 PubMed

Ghrelin Mimetics Show Promise in Reducing Visceral and Somatic Pain

Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics.

Background

Chronic pain, encompassing visceral pain (from internal organs) and somatic pain (from skin, muscles, joints), significantly impacts quality of life and healthcare costs. Current pain treatments often have side effects or are insufficient for complex syndromes like irritable bowel syndrome (IBS). There's a critical need for novel, non-opioid pain management strategies. This study addresses the potential of ghrelin mimetics to modulate pain perception, exploring their efficacy in attenuating both visceral and somatic nociception.


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Source: pubmed:32801950 · Ingested 2026-04-03 · Digest: gemini-2.5-flash