113 studies (1 from unattributed sources) on Mots-c curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
Independent certificate-of-analysis evidence from third-party labs — the data behind the studies. Updated as new COAs are verified. Read the full grey-market analysis →
| Manufacturer | Batches | Avg purity | |
|---|---|---|---|
| Unknown vendor (review) | 48 | 99.43% | View COA → |
| Peptaris | 41 | 99.51% | View COA → |
| Simple Peptide | 23 | 99.43% | View COA → |
| Planet Peptide | 22 | 99.44% | View COA → |
| Alpha & Omega | 22 | 99.43% | View COA → |
| Verified Peptides | 20 | 99.56% | View COA → |
| Peptira LLC | 14 | 99.57% | View COA → |
| Elite Research | 13 | 99.48% | View COA → |
Recent certificates: #27998 (99.88%) · #38467 (99.9%) · #39354 (99.55%) · #49830 (99.61%) · #54509 (99.37%) · #56471 (99.87%)
Manufacturers with published third-party certificates of analysis for Mots-c. Open a vendor to see every batch we've verified.
This research highlights Pyrroloquinoline Quinone (PQQ) as a promising therapeutic agent for mitigating radiation-induced lung injury (RILI), a debilitating side effect of cancer radiotherapy. By demonstrating PQQ's a…
Understanding the role of MOTS-c in facilitating plasma membrane repair opens new avenues for therapeutic strategies. Given that cellular membrane damage is a fundamental component of numerous diseases and injuries, m…
This research positions MOTS-c as a novel and highly promising therapeutic candidate for ovarian cancer, offering a new avenue for treatment. By specifically targeting the USP7-LARS1 pathway, MOTS-c introduces a disti…
This research highlights the critical role of genetic predispositions, specifically the MOTS-c K14Q polymorphism, in age-related health decline. Understanding this genetic link could pave the way for personalized medi…
This research highlights MOTS-c's potential as a novel therapeutic agent to enhance the efficacy of existing cancer treatments by overcoming drug resistance, particularly in challenging tumor microenvironments like hy…
These findings are crucial as they identify multiple novel biomarkers that could potentially aid in the early detection and risk stratification of preeclampsia. Understanding the altered expression of VPO1, humanin, M…
This research provides a novel mechanistic understanding of how endurance training improves skeletal muscle mitochondrial function, highlighting MOTS-c as a key player. The findings suggest that circulating MOTS-c lev…
This research highlights MOTS-c as a promising, non-invasive biomarker for the early detection of Diabetic Kidney Disease (DKD) in children with Type 1 Diabetes Mellitus. Identifying DKD earlier could enable more time…
The most significant finding was that MOTS-c administration achieved comparable or superior protective effects to remote ischemic preconditioning in mitigating lung ischemia-reperfusion injury, reducing tissue damage …
This research significantly advances our understanding of MOTS-c as a potent regulator of muscle development and metabolism, highlighting its potential to improve muscle health across different fiber types. The findin…
This research highlights MOTS-c as a promising novel therapeutic candidate for age-related macular degeneration (AMD), addressing the critical need for treatments that target the underlying mitochondrial dysfunction. …
This pilot study positions MOTS-c as a promising novel biomarker for identifying chronic peritoneal dialysis patients at an elevated risk for sarcopenia. Early detection of sarcopenia through such a biomarker could fa…
This research is crucial for understanding the pleiotropic effects (multiple beneficial actions beyond the primary one) of GLP-1RAs and SGLT-2is in diabetes. By elucidating their impact on neurohumoral and mitochondri…
This research highlights MOTS-c as a promising novel therapeutic agent for preventing or treating CPB-induced acute lung injury. By promoting glycolysis through the AMPK-HIF-1α-PFKFB3 pathway, MOTS-c offers a unique m…
This review underscores the immense therapeutic potential of mitochondria-derived peptides as a novel class of agents for treating cardiovascular diseases. By directly targeting mitochondrial dysfunction, MDPs offer a…
Circulating PGC-1α and MOTS-c could serve as novel, non-invasive biomarkers for assessing mitochondrial health, predicting post-operative complications, and stratifying risk in AVR patients. This could enable earlier …
This research highlights MOTS-c's significant potential as a valuable new tool for the early diagnosis and improved management of Myocardial Infarction. Its ability to provide rapid and accurate diagnostic information…
This study provides compelling evidence that MOTS-c offers a robust protective effect against lung ischemia-reperfusion injury through a novel MYH9-dependent mechanism. The identification of MYH9 as a key mediator lin…
This study highlights MOTS-c as a promising therapeutic agent that can effectively combat diabetic liver fibrosis by mimicking the beneficial effects of exercise. Its ability to modulate key anti-fibrotic and antioxid…
The identification of these circulating mitochondrial biomarkers represents a significant advancement in the diagnostic landscape for Acute Coronary Syndrome. These novel markers could enable earlier and more accurate…
This research highlights MOTS-c as a promising novel therapeutic agent for allergic asthma, offering a unique approach by targeting a fundamental aspect of the disease: airway barrier dysfunction and epithelial apopto…
This research provides a critical mechanistic link between maternal obesity and the multigenerational inheritance of MASLD, highlighting mitochondrial dysfunction as a key driver. Understanding this pathway opens new …
This research highlights the significant potential of MOTS-c-modified peptide hydrogels as a novel therapeutic strategy for intervertebral disc degeneration. By enhancing the activity and survival of NP-MSCs, this app…
This study provides novel insights by identifying reduced MOTS-c levels as a potential characteristic of obstructive sleep apnea patients. Given MOTS-c's established role in metabolic health and cellular resilience, t…
The findings underscore the significant therapeutic potential of mitochondrial-derived peptides as a novel class of agents for preventing and treating vascular aging and associated cardiovascular diseases. By targetin…
These findings highlight MOTS-c as a highly promising therapeutic candidate for treating diabetic cardiomyopathy by directly addressing the underlying mitochondrial dysfunction. The ability of MOTS-c to restore fundam…
This research is significant because it suggests that repeated heat stress could serve as a non-pharmacological intervention to influence metabolic and muscular health, particularly during periods of muscle disuse or …
This review significantly advances our understanding of Parkinson's disease by highlighting the previously underappreciated role of mitochondria-derived microproteins (MDPs) as key players in its pathogenesis. The fin…
This research highlights MOTS-c as a promising therapeutic candidate for mitigating sepsis-associated brain injury by directly targeting the blood-brain barrier. The ability of MOTS-c to preserve BBB integrity and red…
This research highlights the immense potential of a novel multi-biomarker panel to revolutionize prostate disease diagnosis and risk stratification. By combining Humanin, GAS5, miR-21, and miR-103, clinicians could ac…
These findings are highly significant as they identify MOTS-c as a critical regulator of pancreatic islet cell senescence, a process implicated in both type 1 and type 2 diabetes. The ability of MOTS-c to reduce senes…
This research highlights the critical role of muscle-fat crosstalk in maintaining metabolic health during aging and provides compelling evidence that its decline can be pharmacologically targeted. The findings suggest…
This research highlights MOTS-c as a promising therapeutic candidate for osteoarthritis, offering a novel approach by simultaneously targeting mitochondrial health, reducing inflammatory cell death, and activating pro…
This comprehensive review highlights MOTS-c as a highly promising therapeutic candidate for Type 2 Diabetes Mellitus (T2DM), offering a multi-pronged approach to combat both metabolic dysfunction and severe cardiac co…
This research highlights MOTS-c as a highly promising therapeutic candidate for intrauterine growth restriction (IUGR), a condition currently plagued by limited effective treatment options. By demonstrating its abilit…
This research highlights the potential of Humanin, Mots-c, and telomere length as novel, non-invasive biomarkers for Alzheimer's disease. Identifying such biomarkers could pave the way for earlier and more accurate di…
This groundbreaking research suggests that circulating MOTS-c could serve as a powerful new diagnostic and prognostic biomarker for Acute Coronary Syndrome and Major Cardiac Events. The ability to identify patients at…
This review establishes a crucial link between mitochondrial-derived microproteins and the pathogenesis of both cancer and neurodegenerative diseases, offering a novel perspective on disease etiology. By identifying c…
This research positions MOTS-c as a highly promising complementary biomarker for assessing treatment response in Multiple Myeloma, offering a novel avenue for patient monitoring. Its dynamic changes could enable earli…
This research highlights MOTS-c as a potent activator of muscle mitochondrial function, offering a novel therapeutic strategy for conditions characterized by mitochondrial dysfunction and muscle decline. By improving …
This review significantly advances our understanding of mitochondria-derived peptides (MDPs) as critical regulators of hepatic metabolism and potential therapeutic agents. The identification of MDPs like MOTS-c and Hu…
These findings suggest that elevated MOTS-c could serve as a novel biomarker for obesity-associated metabolic dysregulation, potentially identifying individuals at higher risk for complications. The persistence of hig…
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