Mgf Purity: 18 Lab Tests Across 8 Identified Manufacturers
186 studies on Mgf curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
Bottom line: TitrateLab currently tracks 18 published third-party lab tests of Mgf across 8 identified manufacturers. Among reports with a positive numeric purity result, the average is 99.66%. Within this published corpus, 0 positive purity results were below 90%, and 2 reports showed measured quantity more than 10% below the label claim. These are batch-level observations, not guarantees of product identity, safety, or vendor quality.
We tested 18 Mgf batches across 8 identified manufacturers
Independent certificate-of-analysis evidence from third-party labs — the data behind the studies. Updated as new COAs are verified. Read the full grey-market analysis →
Within that total, 4 batches have unresolved manufacturer identity. They remain in corpus-level lab evidence and are excluded from named-manufacturer rankings.
Top 3 vendor evidence profiles for Mgf
Eligible vendors have at least 2 deduplicated tests and 2 classifiable identity observations. Rank uses the 95% lower confidence bound on clean identity results; mean positive purity and test count break ties. Missing measurements are not passes. Exact-zero/not-detected and explicit wrong-compound markers count once per adverse certificate. This describes tested batches, not every product or shipment, and is not an endorsement.
| Rank | Manufacturer | Tests | Avg positive purity | Identity adverse results | |
|---|---|---|---|---|---|
| #1 | 4 | 99.72% | 0 of 4 (0.0%) 0 0% / not detected · 0 wrong compound | Reveal with Pro → | |
| #2 | 4 | 99.72% | 0 of 4 (0.0%) 0 0% / not detected · 0 wrong compound | Reveal with Pro → |
Manufacturer identities are included with Pro. Batch counts and lab measurements remain visible.
Recent certificates: #75094 (99.624%) · #84919 (99.648%) · #86307 (99.95%) · #90666 (99.95%) · #15169 (99.491%) · #46295 (99.873%)
Mgf studies and clinical research
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Low IGF-1 levels amplify cardio-kidney risk in MASLD patients, UK Biobank data shows
This study provides compelling evidence that **incorporating IGF-1 levels into clinical evaluations can significantly improve risk stratification for MASLD patients**, particularly concerning their cardio-kidney healt…
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IMC-A12 safety and optimal dose explored in advanced cancer patients unresponsive to standard treatments
IMC-A12's safety and optimal dosing are being evaluated in participants with advanced tumors resistant to current therapies.
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Dose-ranging study aims to identify optimal recombinant human IGF-I for pediatric hyperinsulinism
While specific findings are not available from this abstract, the study's objective highlights a critical need for novel therapies in **hyperinsulinism**. **Recombinant human IGF-I** represents a promising avenue, pot…
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Growth Hormone Administration Significantly Elevates GH and IGF-I Levels in Healthy Individuals
GH administration in healthy volunteers boosted mean GH levels by **46%** and IGF-I levels by **45%**, with basal GH increasing **7.5-fold**.
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GH Dosing in GHD Adults: Investigating IGF-I's U-shaped Association with Cardiovascular Risk Factors
An open-label RCT will investigate how varying **Growth Hormone** doses, targeting different IGF-I levels, impact cardiovascular risk factors in **GHD** adults.
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Washed Microbiota Transplantation Explored as a Strategy for Non-Immune Food Intolerance
Washed microbiota transplantation (WMT) is under investigation as a novel therapeutic approach for **food intolerance (FI)**, a common non-immune adverse food reaction affecting 20% of the global population.
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French National Registry Describes Somatropin Efficacy, Safety, and Compliance in GHD Adults
**Real-world data from national registries are critical for understanding the long-term impact of somatropin therapy in diverse patient populations.** This registry provides a framework to monitor the effectiveness an…
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Green Tea Extract Studied for Breast Cancer Prevention in High-Density Postmenopausal Women
**Identifying natural, well-tolerated agents for breast cancer prevention is crucial**, especially for high-risk postmenopausal women seeking alternatives to pharmaceutical interventions. If green tea extract demonstr…
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JNJ-42847922's Antidepressant Mechanism Explored in MDD Participants Based on Hyper-Arousal Status
This study's findings, once available, could significantly advance our understanding of personalized treatment approaches for **Major Depressive Disorder**. If the antidepressant efficacy of **JNJ-42847922** is indeed…
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L-arginine's Impact on Microcirculation, Myogenesis, and Angiogenesis in Older Women with Sarcopenia and Diabetes Investigated
Study evaluates 5g oral **L-arginine** daily for 14 days on microcirculation and muscle health in older women with sarcopenia or T2DM.
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Recombinant Human Growth Hormone Trial Evaluates Efficacy, Safety for Idiopathic Short Stature in Korea
Establishing the efficacy and safety of **recombinant human growth hormone** within the Korean population affected by **idiopathic short stature** is paramount for optimizing clinical management. Positive findings fro…
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Combined Resistance and Aerobic Training Improves Post-Stroke Cognition, Mobility Over Aerobic Training Alone
If combined training proves superior, it could significantly reshape **post-stroke rehabilitation protocols**, offering a more effective strategy for improving patient outcomes. This would mean moving beyond tradition…
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Increlex Proposed to Treat Growth Failure in Children with Chronic Liver Disease
Increlex (IGF-1) is proposed to address growth failure in children with chronic liver disease, a condition resistant to traditional growth hormone therapy.
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SAGIT® instrument validation study launched to standardize acromegaly disease activity and staging
SAGIT® instrument validation study aims to define and validate its scoring for managing **acromegaly** patients and disease activity.
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Growth Hormone and Secretagogues Modulate Bone Physiology via IGF-1 Axis
The GH/IGF-1 axis is crucial for bone health, with growth hormone and its secretagogues influencing bone development and maintenance.
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Serum IGF-1 Dynamic Changes Post-Intracerebral Hemorrhage Explored for Prognostic Correlation
While the abstract does not present specific findings, the *aim* of this research highlights the critical need for improved prognostic biomarkers in **intracerebral hemorrhage (ICH)**. If future full publications from…
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ACRODAT software initiates prospective evaluation to improve acromegaly treatment outcomes
ACRODAT® software, using 5 key parameters, is undergoing prospective evaluation to determine if it improves acromegaly treatment outcomes.
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Low-glycemic-load and milk-free diet's effect on acne severity to be assessed via mTORC pathway
If this study demonstrates that a **low-glycemic-load and milk-free diet significantly reduces acne severity**, it could offer a powerful, non-pharmacological intervention for individuals struggling with **acne**. Thi…
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Efficacy of Premium Revitalizing Elixir, containing IGF-1 and FGF-7, to be assessed for scalp health
A randomized, double-blinded, placebo-controlled study will evaluate Premium Revitalizing Elixir containing IGF-1, FGF-7, caffeine, and panthenol for scalp care efficacy in 60 adults with hair thinning.
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DHEA and Estrogen Replacement Trial Investigates Bone Loss in Young Women with Anorexia Nervosa
The severe **bone loss** associated with **anorexia nervosa** represents a critical unmet medical need, often leading to irreversible skeletal damage. If this trial demonstrates that **DHEA** and **estrogen replacemen…
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Low-dose growth hormone hypothesized to reduce visceral fat in HIV lipodystrophy patients
Low-dose growth hormone was hypothesized to reduce visceral fat in HIV lipodystrophy patients, with secondary endpoints including IGF-1, glucose, and lipids.
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Pasireotide LAR and Octreotide LAR Efficacy Compared for GH/IGF-1 Normalization in Active Acromegaly
While this specific trial yielded no data due to its withdrawal, the underlying clinical question remains highly relevant for patients with **acromegaly**. Identifying more effective or alternative somatostatin analog…
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Somapacitan Once-Weekly Compared to Daily Norditropin® for Pediatric Growth Hormone Deficiency in Phase 3 Trial
A successful once-weekly growth hormone therapy like somapacitan could significantly **reduce the treatment burden for children with GHD and their caregivers**, potentially leading to improved adherence and better lon…
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Pulsed Electromagnetic Field (PEMF) Trial Aims to Alleviate Knee Osteoarthritis Pain and Improve Function
A double-blinded RCT will investigate if **PEMF treatment** can reduce pain and improve knee function in older adults with **knee osteoarthritis**.
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PF-05231023 intravenous doses evaluated for preliminary safety and tolerability in Type 2 Diabetes
PF-05231023's safety, tolerability, pharmacokinetics, and pharmacodynamics were assessed in a Phase 1 study in adult subjects with **Type 2 Diabetes**.
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IGF-I Investigated for Impact on Body Composition, Glucose, and Lipids in HIV Metabolic Disease
Understanding the role of **IGF-I in mitigating HIV metabolic disease** could offer a novel therapeutic avenue for a challenging patient population. If IGF-I proves effective in improving body composition, glucose con…
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PEG-somatropin Injection Dose-Finding, Safety, and Efficacy Study Initiated for Pediatric Turner Syndrome
Phase 3 study initiated to determine optimal dose, safety, and efficacy of **PEG-somatropin** injection for children with **Turner Syndrome**.
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Debio 4126 assessed for IGF-1 maintenance in acromegaly patients previously treated with somatostatin analogs
If successful, this study could introduce a new therapeutic option for **acromegaly** patients who struggle to achieve or maintain `IGF-1` normalization with existing somatostatin analogs. A novel somatostatin analog …
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Enteral zinc supplementation hypothesized to improve growth in infants at risk for bronchopulmonary dysplasia
Enteral zinc supplementation is hypothesized to improve growth in infants at risk for bronchopulmonary dysplasia, potentially addressing persistent growth deficits.
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Cod Bone Calcium-Binding Peptide Isolated via Novel Chromatography for Chelation and Transport Evaluation
A novel static affinity chromatography strategy was developed to isolate a **cod bone calcium-binding peptide**, enabling evaluation of its chelation mechanism and calcium transport.
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Once-weekly ACP-001 (TransCon hGH) safety, PK, and PD profile evaluated against daily hGH in adults with GHD
While specific results are not detailed in this abstract, the investigation of **ACP-001 (TransCon hGH)** represents a crucial step towards improving **GHD** treatment. If successful, a once-weekly growth hormone coul…
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Lanreotide Autogel 120mg dose intervals (28, 42, 56 days) evaluated for acromegaly efficacy and safety
Lanreotide Autogel 120mg at 28, 42, or 56-day intervals was evaluated for efficacy and safety in acromegaly patients, compared to previous octreotide LAR.
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Mecasermin (rhIGF-1) long-term safety and effectiveness evaluated in children with Primary IGF-1 Deficiency
A Phase 3 extension study evaluated the long-term safety and effectiveness of mecasermin (rhIGF-1) in children with severe Primary IGF-1 Deficiency.
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Six-month resistance training trial investigates brain and muscle health in older adults with MCI
If successful, this trial could establish **progressive resistance training** as a crucial non-pharmacological intervention for managing **mild cognitive impairment (MCI)**, potentially delaying its progression to dem…
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Apulian Lens Culinaris supplement aims to reduce sarcopenia and uremic toxins in dialysis patients
A pilot study evaluates an **Apulian Lens Culinaris**-based supplement for reducing **sarcopenia**, uremic toxins, and inflammation in dialysis patients.
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Milk Protein and Vitamin D Study Investigates Combined Effects on Child Growth, Bone Health, and Metabolism
This study, once completed and published, holds significant implications for pediatric nutrition and public health. If positive, the findings could **inform new dietary guidelines for children**, potentially recommend…
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Acromegaly screening protocol established to define prevalence in associated somatic disorders
This defined screening protocol offers a crucial framework for **systematic identification of acromegaly** in patients with pre-existing somatic disorders, particularly those with conditions like **type 2 diabetes**. …
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Framingham State Food Study to investigate dietary composition's impact on energy expenditure and chronic disease risk
A planned Framingham State Food Study will evaluate how dietary composition influences energy expenditure and chronic disease risk factors, aiming to inform nutritional recommendations.
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Clomiphene Citrate Investigated for Refractory Acromegaly in Male Patients
**Clomiphene citrate**'s effect on serum `IGF-1` and testosterone is being assessed in male **acromegaly** patients whose condition remains uncontrolled by conventional treatments.
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Growth Hormone Axis Dynamics Investigated Across Progressive Stages of Nonalcoholic Fatty Liver Disease
Understanding the precise dynamics of the **growth hormone axis** in progressive **Nonalcoholic Fatty Liver Disease** (NAFLD) could reveal critical biomarkers for disease severity or progression. If the hypothesized r…
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Somatropin Efficacy to be Evaluated in Adults with Trauma-Induced Growth Hormone Deficiency
A study will assess somatropin's efficacy in treating **Growth Hormone Deficiency (GHD)** in adults following head injury or major trauma, and determine prevalence.
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Recombinant human growth hormone (r-hGH) evaluated for severe fibromyalgia with growth axis dysfunction
**Investigating growth hormone axis dysfunction in fibromyalgia is crucial for identifying novel therapeutic targets beyond symptomatic relief.** If r-hGH proves effective, it could offer a physiological approach to m…
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Prospective cohort studies PN cessation timing, IGF-1, and growth in VLBW infants
A prospective cohort aims to estimate how parenteral nutrition cessation timing and IGF-1 influence growth in very low birth weight infants.
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Proposed Study to Uncover Insulin Signaling's Role in ALS Motor Neuron Reinnervation and Muscle Function
Understanding the contribution of **insulin signaling** to motor neuron reinnervation in **ALS** could unlock entirely new therapeutic strategies. If successful, this research may identify novel targets beyond current…
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HIIT program investigated for improving quality of life, executive functions, and IGF-1 in sedentary young women
If a **HIIT program** proves effective, it could offer a highly accessible and non-pharmacological strategy to significantly improve **quality of life**, **executive functions**, and **IGF-1** levels in sedentary youn…
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Diabetic Chronic Periodontitis Hypothesized to Alter Platelet-Rich Fibrin (PRF) Growth Factor Release
If the hypothesis regarding altered **PRF growth factor** release in **diabetic patients** with **chronic periodontitis** is substantiated, it would fundamentally change how regenerative dental procedures are approach…
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CP-751,871, an IGF-1R inhibitor, investigated with chemotherapy for advanced NSCLC survival
**Targeting the `IGF-1R` pathway represents a significant strategy for improving outcomes in advanced `NSCLC`**, a disease with high unmet medical need. If **CP-751,871** demonstrated a survival benefit, it could pave…
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Trial to investigate creatine and resistance training effects on cognition in older adults with mild cognitive impairment
**If successful, this trial could establish creatine and resistance training as evidence-based, non-pharmacological interventions for mild cognitive impairment.** This would offer accessible strategies to potentially …
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Phase 1 study assesses CP-751,871 with docetaxel in advanced non-hematologic malignancies
**Combining targeted therapies with traditional chemotherapy** represents a promising strategy to improve patient outcomes in **advanced non-hematologic malignancies**. If **CP-751,871** can safely enhance docetaxel's…
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Time-Restricted Feeding Trial Initiated to Assess Metabolic and Endocrine Effects in Overweight Women with PCOS
A 6-week single-arm trial will investigate time-restricted feeding's impact on endocrine and metabolic profiles in overweight women with **Polycystic Ovary Syndrome (PCOS)**.
Research tools
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