Side-by-side research comparison of MOTS-c and SS-31 across our PubMed, ClinicalTrials.gov, and EuropePMC corpus. 3 head-to-head studies plus 121 on MOTS-c and 98 on SS-31.
| MOTS-c | SS-31 | |
|---|---|---|
| Drug class | mitochondrial peptide | mitochondrial peptide |
| Studies in corpus | 121 | 98 |
| Highest evidence tier | meta analysis | cohort |
| Evidence tier mix | other · 36 review · 9 cohort · 6 preclinical animal · 37 in vitro · 8 meta analysis · 1 | preclinical animal · 37 review · 15 other · 14 cohort · 1 in vitro · 14 case report · 1 case series · 1 |
| Studies with explicit sample size | 1 | 1 |
| Head-to-head studies in corpus | 3 | |
Beyond the literature: here's what third-party Certificate-of-Analysis records (Janoshik, BCC, Auxlabs) say about real MOTS-c and SS-31 batches we've tested. Aggregate, public data — cross-reference against the studies below.
We tested 3692 MOTS-c batches across 1278 manufacturers, 99.46% avg purity.
We tested 1601 SS-31 batches across 663 manufacturers, 99.79% avg purity.
We hold deeper lab coverage on MOTS-c (3692 batches tested). SS-31 edges ahead on average measured purity (99.46% vs 99.79%) — a narrow gap; weigh it against failed-batch and underdose counts above.
Studies in our corpus that mention both MOTS-c and SS-31 — the gold-standard direct comparison evidence.
The findings underscore the significant therapeutic potential of mitochondrial-derived peptides as a novel class of agents for preventing and treating vascular aging and associated cardiovascular diseases. By targeting fundamental cellular processes like mi…
This review significantly advances our understanding of mitochondria-derived peptides (MDPs) as critical regulators of hepatic metabolism and potential therapeutic agents. The identification of MDPs like MOTS-c and Humanin as key players in combating liver …
This review underscores the immense therapeutic potential of mitochondria-derived peptides as a novel class of agents for treating cardiovascular diseases. By directly targeting mitochondrial dysfunction, MDPs offer a unique approach to not only manage symp…
Looking for vendor-level purity, endotoxin, and HPLC data on MOTS-c or SS-31? TitrateLab tracks Certificate-of-Analysis records from the major peptide labs (Janoshik, BCC, Auxlabs) alongside the research above. Cross-reference vendor batches against the studies on this page.