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MOTS-c 2026-10-27 PubMed

MOTS-c attenuates placental vascular endothelial cell apoptosis in ICP by inhibiting K33-linked deubiquitination of BACH1

MOTS-c attenuates placental vascular endothelial cell apoptosis in intrahepatic cholestasis of pregnancy by inhibiting K33-linked deubiquitination of BACH1.

Abstract

MOTS-c significantly reduced placental vascular endothelial cell apoptosis and improved fetal outcomes in a murine ICP model by promoting BACH1 degradation.

TitrateLab articles covering MOTS-c

Written by TitrateLab, separately from the study summarized above.


Source: pubmed:42934731 · Ingested Oct 27, 2026 · Digest: gemini-2.5-flash