GHK-Cu: A Copper Peptide with Diverse Regenerative Potential

The tripeptide GHK (glycyl-L-histidyl-L-lysine) naturally occurs in human plasma, saliva, and urine, playing a crucial role in wound healing, tissue regeneration, and anti-inflammatory processes. Its complex with copper, GHK-Cu, enhances its bioavailability and activity, making it a subject of interest for therapeutic applications. Despite extensive in vitro and anecdotal evidence, the precise mechanisms and efficacy of GHK-Cu in specific in vivo models for skin repair and anti-aging remain an active area of investigation.