71 studies on Selank curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
Precise chemical characterization is fundamental for any therapeutic agent, ensuring reproducibility in research and safety in potential clinical applications. Understanding Selank's exact molecular structure allows f…
Understanding the acute cognitive impacts of high-altitude hypoxia is crucial for safety and performance in various contexts, including mountaineering, military operations, and occupational tasks in high-altitude envi…
The successful demonstration of efficacy for either tDCS or tRNS could represent a significant breakthrough in the management of developmental dyslexia. If proven effective, these non-invasive brain stimulation techni…
This study provides compelling and quantitative evidence that Selank possesses the capability to effectively compensate for the long-lasting negative effects of antenatal hypoxia on both integrative brain activity and…
This research highlights Selank's potential as a novel anxiolytic or antipsychotic agent that can modulate dopamine system activity without directly binding to dopamine receptors, potentially offering a therapeutic pr…
This research provides compelling evidence for the anti-ulcer properties of Selank, suggesting its potential beyond its known anxiolytic (anti-anxiety) effects. The fact that its metabolites also contribute to this pr…
This study provides compelling evidence that Selank holds significant promise as a therapeutic agent for addressing the long-term neurological consequences of antenatal hypoxia. The ability to correct deficits in sens…
This research highlights Selank's potential as a novel therapeutic agent for Generalized Anxiety Disorder and neurasthenia, offering a dual benefit of anxiety reduction alongside anti-fatigue and psychostimulant effec…
This research highlights Selank's significant potential as a neuroprotective and cognitive-enhancing agent, particularly in conditions involving noradrenergic system dysfunction. Given that cognitive deficits are a ha…
These findings suggest that Selank possesses unique immunomodulatory properties, acting as a novel regulator of the immune response. This dual effect on IL-6 gene expression and protein concentration, alongside its im…
These findings are highly significant as they demonstrate Selank's broad efficacy against both genetically-based and situation-provoked symptoms of depression and anxiety. Its ability to act as an anxiolytic and antid…
This research highlights the significant potential of Selank as a therapeutic agent for cognitive impairments resulting from early-life neurological damage. The ability of Selank to restore complex cognitive functions…
This research provides critical and actionable insights into the pharmacokinetics of glyprolines, underscoring that the chosen route of administration profoundly dictates their bioavailability to key target organs suc…
This research provides compelling evidence for Selank's potential as a broad-spectrum therapeutic agent for psychoemotional disturbances. Its ability to induce long-term compensation of both behavioral and cognitive d…
This research provides crucial insights into the pharmacogenomic variability of peptide therapeutics, demonstrating how genetic background can profoundly influence drug efficacy and mechanism of action. Understanding …
This study provides compelling evidence that MIF and Selank possess significant neuroprotective and anti-inflammatory properties in the context of hemorrhagic stroke. The observed improvements in neurological function…
This research underscores selank's potential as a promising therapeutic agent for conditions characterized by decreased serotonin metabolism. The observed ability of selank to rapidly enhance 5-HT metabolism in the br…
These findings highlight Selank's potential as a novel antiviral agent, particularly for influenza prevention. The ability of Selank to modulate the immune response by selectively upregulating IFN-alpha suggests a tar…
This research provides compelling evidence that Selank acts as a potent nootropic agent, significantly enhancing long-term memory stability. The observed modulation of serotonin metabolism offers a plausible mechanism…
This research provides compelling evidence that altered long-distance neural communication, specifically within the gamma frequency band, is a persistent neurobiological feature of bipolar disorder, even when patients…
This research provides compelling evidence that Selank possesses potent immunomodulatory properties, extending beyond its known neurological effects, by directly influencing the transcriptional activity of key inflamm…
This research significantly advances our understanding of Selank's mechanism of action, particularly its immunomodulating effects at the genetic level. Identifying Gly-Pro as a key pharmacophor for these effects opens…
This study provides a crucial mechanistic understanding of how Noopept and Selank exert their nootropic and anxiolytic effects by enhancing inhibitory neurotransmission in the hippocampus. By demonstrating that these …
This research identifies the enkephalin-opioid system as a critical modulator of Selank's anxiolytic actions, revealing a new dimension to its mechanism within the central nervous system (CNS). Understanding this intr…
This research provides a potential biochemical mechanism for Selank's known anxiolytic and nootropic effects. By modulating the activity of carboxypeptidases, Selank could directly influence the production and availab…
This research highlights Selank's potential as a promising therapeutic agent for cognitive enhancement and the treatment of memory impairment. Given its ability to counteract deficits caused by protein synthesis inhib…
This research highlights Selank's potent and time-dependent immunomodulatory properties, specifically its ability to rapidly downregulate key pro-inflammatory gene expression. Understanding these temporary dynamics is…
This research provides crucial molecular insights into how Selank exerts its nootropic effects, linking its action to fundamental cellular processes like ion homeostasis and membrane protein function. Understanding th…
This research highlights Selank as a promising anxiolytic peptide with potential to specifically alleviate the distressing symptoms of Alcohol Withdrawal Syndrome (AWS). The ability of Selank to reduce both anxiety an…
This research significantly extends therapeutic possibilities for managing anxiety disorders by introducing Selank as a potentially superior alternative to traditional anxiolytics. The peptide's prolonged anxiolytic e…
This study provides compelling evidence that periodized strength training is more effective than non-periodized training for eliciting early adaptations in both strength and muscle hypertrophy in recreational males. T…
This research is significant because it suggests Selank could provide a novel and effective option for managing anxiety disorders, potentially offering a better side-effect profile and improved tolerability compared t…
This study underscores the critical importance of administration route and genetic background in determining the pharmacological profile and efficacy of peptide therapeutics like Selank. The observed differences in on…
This research provides crucial mechanistic insights into how Selank exerts its anxiolytic and neuroprotective effects by directly modulating gene expression within the GABAergic system. Understanding these specific ge…
The study revealed that Selank at 0.3 mg/kg effectively prevented the development of ethanol-induced hyperlocomotion, demonstrating a clear inhibitory effect on this stimulant behavior. This effect was similar to that…
This study provides compelling evidence that Selank can act as an effective adjunct therapy, significantly enhancing the anxiolytic effects of traditional benzodiazepines like diazepam. This synergistic interaction co…
This research provides crucial insights into the molecular mechanisms by which GABA, Selank, and Olanzapine influence GABAergic neurotransmission, highlighting their diverse pharmacological profiles. The discovery tha…
This research provides crucial insights into the neurobiological mechanisms underlying Selank's known anxiolytic (anti-anxiety) properties. By specifically boosting inhibitory signals in the hippocampus, a brain regio…
This research highlights the potential of Selank as a therapeutic agent for managing non-motor symptoms, specifically anxiety, in Parkinson's disease, even in the presence of significant neurodegeneration. The fact th…
This study provides compelling evidence that Selank possesses significant hepatoprotective and antioxidant properties, effectively shielding the liver from the damaging effects of both acute and chronic restraint stre…
The identification of potent anticoagulant effects from glyproline peptides, particularly Selank, represents a significant step towards developing novel antithrombotic agents. Current anticoagulants often come with a …
This study provides crucial evidence that the Roche cobas hrHPV test maintains robust performance across the two most common liquid-based Pap test platforms, ThinPrep and SurePath. This consistency is vital for labora…
This research significantly advances our understanding of Selank's mechanism of action, highlighting its potential as a novel peptide-based anxiolytic with a favorable molecular profile. By modulating both GABAergic a…
This research is pivotal for enhancing animal welfare standards and sustainability within the organic poultry sector. By quantifying the extent of foot pad dermatitis, the study provides actionable data for farmers, v…
This research significantly expands the synthetic toolbox for creating bimetallic complexes featuring the unique isoselenocarbonyl ligand. The successful structural characterization of three new complexes (4, 5, and 7…
This research highlights Selank's potential as a therapeutic agent for managing stress-induced gut dysbiosis, which is increasingly recognized as a contributor to various health issues, including mental health disorde…