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selank anxiolytic other 2023-05-01 ClinicalTrials

Brain Stimulation for Dyslexia: Comparing tDCS and tRNS Efficacy in Children

Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia

Background

Children and adolescents with developmental dyslexia (DD) often struggle with reading skills, impacting their academic and daily lives. Despite its prevalence, there is currently an absence of robust, evidence-based treatments specifically designed to effectively improve reading in individuals with DD. This study aims to address this critical gap by exploring novel therapeutic avenues.

Results

As this is an ongoing study protocol (NCT ID: NCT05832060), specific results are not yet available. The investigators hypothesize that both active tRNS and active tDCS applied over the temporo-parietal cortex (TPC) will significantly improve reading skills in children and adolescents with DD. They anticipate that sham stimulation will show no significant effect on reading skills, thereby establishing a clear distinction between active and placebo interventions. The study's completion is projected for March 2025, at which point quantitative data on improvements in reading skills will be analyzed and reported, comparing the active tDCS and tRNS groups to the sham control.

Why It Matters

The successful demonstration of efficacy for either tDCS or tRNS could represent a significant breakthrough in the management of developmental dyslexia. If proven effective, these non-invasive brain stimulation techniques could lead to a new, evidence-based therapeutic approach for improving reading skills in affected children and adolescents. This would offer a much-needed alternative or adjunct to current educational interventions, potentially paving the way for larger Phase II or Phase III human trials and broader clinical adoption.


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Source: clinicaltrials:NCT05832060 · Ingested 2026-04-03 · Digest: gemini-2.5-flash