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mots-c mitochondrial peptide review 2026-04-23 EuropePMC

Mitochondria-Targeted Nanotechnology Shows Promise for Heart Disease Treatment

Mitochondria-targeted nanotechnology in cardiovascular diseases: a review of recent advances

Background

Cardiovascular diseases (CVDs), including myocardial infarction and heart failure, remain leading causes of mortality worldwide. A key contributor to their progression is mitochondrial dysfunction, where the cell's powerhouses fail, leading to cellular damage and death. Traditional therapies often lack specificity, leading to off-target effects. This review addresses the recent advances in using nanotechnology to specifically target mitochondria for therapeutic intervention in CVDs.


mots-c mitochondrial peptide
Source: europepmc:epmc_PMC13095658 · Ingested 2026-04-23 · Digest: gemini-2.5-flash