Humanin Variants Differentially Regulate BID Fibrilization, Suppressing BAX- and BID-Dependent Membrane Permeabilization
Humanin variants differentially regulate BID fibrilization and suppress BAX- and BID-dependent membrane permeabilization.
Abstract
Humanin variants differentially regulate BID fibrilization, with specific residues dictating interactions, ultimately suppressing BAX- and tBID-mediated membrane permeabilization. This clarifies HN's cytoprotective mechanism.