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Oxytocin 2026-07-06 PubMed

Foley Catheter Safely and Effectively Induces Labor Across All Trimesters, Achieving 100% Success in First and Second Trimesters.

Foley Catheter for Cervical Ripening Across Gestational Ages: A Retrospective Descriptive Study in a Resource-Limited Setting.

Background

Labor induction or pregnancy termination is a frequent obstetric intervention, often critical when continued pregnancy poses risks to maternal or fetal health. While pharmacologic agents like prostaglandins are commonly used, they carry risks such as uterine hyperstimulation, which can be detrimental. In contrast, mechanical cervical ripening using a Foley catheter has garnered renewed interest due to its favorable safety profile, low cost, and ease of use. This method offers a crucial alternative, particularly in resource-limited settings or when pharmacologic options are unavailable, addressing a significant gap in accessible and safe induction strategies.

Study Design

This retrospective descriptive study was conducted at Mohammed VI University Hospital in Marrakesh, Morocco, from October 2024 to February 2025, involving 104 patients. The cohort comprised 37 patients in the first trimester (T1), 14 in the second trimester (T2), and 53 in the third trimester (T3). For cervical ripening, a 16-18-Fr Foley catheter was inserted and inflated with 50-60 mL saline. In T3, oxytocin infusion was administered after catheter expulsion or removal, whereas in T1 and T2, the catheter served as the sole induction method. Evaluated endpoints included induction time intervals, success rates, maternal morbidity, and neonatal outcomes.

Results

The study demonstrated high efficacy and safety for Foley catheter induction across all gestational trimesters. Among the 104 patients, a significant 72.1% initiated labor within 12 hours of catheter insertion, indicating rapid onset of cervical changes. The mean induction-to-expulsion/delivery interval varied by trimester: 17.5±7.2 hours in T1, 16.8±6.8 hours in T2, and 12.2±5.4 hours in T3, with T3 showing the shortest interval. Maternal morbidity was reported as low, with no maternal deaths occurring across the entire cohort. For live births in T3, 77.1% of neonates achieved an Apgar score of ≥8 at five minutes, reflecting generally favorable neonatal conditions despite the induction process. These findings underscore the Foley catheter's potential as a reliable and safe method for cervical ripening and labor induction.

Key Findings

  • 72.1% of patients initiated labor within 12 hours of Foley catheter insertion.
  • Induction success rates reached 100% in the first and second trimesters.
  • Third-trimester induction success was 94.3% (50/53) with Foley catheter.
  • Mean induction-to-delivery interval was shortest in T3 at 12.2±5.4 hours.
  • Maternal morbidity was low, with no maternal deaths reported.

Why It Matters

Foley catheter mechanical induction offers a highly feasible and safe strategy for labor induction across all gestational trimesters, particularly vital in resource-limited settings where pharmacologic agents may be scarce or cost-prohibitive. This study reinforces the clinical utility of a simple, low-cost intervention as a primary method for cervical ripening, providing a robust alternative to prostaglandins. For clinicians, this means a reliable, accessible tool to manage labor induction, potentially reducing reliance on more complex or expensive pharmacological protocols. The high success rates and low morbidity observed suggest that this method can improve maternal and neonatal outcomes in diverse healthcare environments, making it a critical consideration for standard obstetric practice.


Source: pubmed:42403813 · Ingested 2026-07-06 · Digest: gemini-2.5-flash