Oroxylin A suppresses LL-37-induced rosacea-like skin inflammation by modulating `SIRT3-SOD2-NF-κB` signaling
Corrigendum to "Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF-κB signaling pathway" [Int. Immunopharmacol. 129 (2024) 111636].
Background
Rosacea is a chronic inflammatory skin condition characterized by erythema, telangiectasias, and papulopustular lesions, often triggered by the antimicrobial peptide LL-37. Current treatments primarily manage symptoms but lack targeted mechanisms for LL-37-induced inflammation. Understanding novel pathways, such as SIRT3-SOD2-NF-κB signaling, offers potential for more effective therapeutic strategies. This research explores Oroxylin A as a candidate for targeting this specific inflammatory cascade.