MOTS-c: A Detailed Chemical Profile from PubChem Database
Background
MOTS-c is a mitochondrial-derived peptide, often studied for its roles in metabolic regulation, cellular energy homeostasis, and stress response. While it holds significant promise in areas like type 2 diabetes and obesity, the provided record focuses exclusively on its fundamental chemical identification. This entry specifically details the molecular structure and identifiers of MOTS-c as cataloged in the PubChem database, rather than experimental findings.
Results
The PubChem profile for MOTS-c provides its unique chemical identifiers and structural composition. It lists the Compound ID (CID) as 146675088, a standard numerical identifier for chemical substances in the PubChem database. The molecular formula is precisely defined as C101H152N28O22S2, indicating the exact atomic composition of the peptide, comprising 101 carbon, 152 hydrogen, 28 nitrogen, 22 oxygen, and 2 sulfur atoms. The molecular weight of MOTS-c is precisely recorded as 2174.6 g/mol, a critical parameter for its characterization and synthesis. Additionally, the profile includes the full IUPAC Name, a systematic nomenclature for its complex peptide structure, and its InChIKey (International Chemical Identifier Key), WYTHCOXVWRKRAH-LOKRTKBUSA-N, a hashed version of the InChI that allows for easy web searching of chemical structures. These details are essential for unambiguous identification and comparison across scientific literature.
Why It Matters
This detailed chemical profile is crucial for the unambiguous identification and characterization of MOTS-c in research and development. Accurate chemical identification is the bedrock for all subsequent experimental work, ensuring researchers are studying the correct compound and can replicate synthesis or purification methods. While this record does not present new biological findings, it provides the essential chemical blueprint necessary for future studies, including in vitro assays, in vivo animal models, and ultimately, potential human clinical trials. It underpins the ability to synthesize, analyze, and understand the physical properties of this important peptide.