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Oxytocin 2013-07 ClinicalTrials

Immediate Skin-to-Skin Contact Post-C-Section Hypothesized to Reduce Maternal Stress Markers, Elevate Oxytocin

Pilot Study: Sectio Bonding/Early Skin-to-skin Contact (SSC) After Caesarean Section

Background

Cesarean section (CS) rates have increased significantly, often delaying crucial early skin-to-skin contact (SSC) compared to vaginal deliveries. This immediate post-birth period is vital for maternal-infant bonding and physiological adaptation. Current practice often postpones SSC until after the operation concludes, missing a critical window. Concerns like operating room ambiance (temperature, light, noise) and established processes hinder immediate SSC adoption, despite evidence from a Cochrane review supporting its positive effects. This pilot study addresses the gap by investigating the direct physiological impact of immediate SSC in the OR.

Study Design

This prospective randomized pilot trial will analyze the effects of early skin-to-skin contact (SSC) immediately after Cesarean section in the operating room. Mothers randomized to the intervention arm will receive SSC directly after birth, while controls will follow standard post-operative procedures. Primary endpoints include maternal levels of cortisol, chromogranin A, alpha amylase, and oxytocin. Newborn adaptation will be assessed to ensure it remains within normal ranges. Secondary outcomes will evaluate effects on breastfeeding, maternal pain processing, and mental health.

Results

This abstract describes the hypothesis for a pilot study, not actual findings. Researchers hypothesize that mothers receiving immediate early skin-to-skin contact (SSC) in the operating room will exhibit lower levels of stress biomarkers, specifically cortisol, chromogranin A, and alpha amylase. > They also expect to observe higher maternal oxytocin levels in the immediate SSC group. Furthermore, the study aims to confirm that newborn adaptation remains within normal physiological ranges under immediate SSC conditions. Additional hypothesized benefits include positive effects on breastfeeding, maternal pain processing, and overall mental health. No quantitative results or statistical significance values are reported in this protocol description.

Why It Matters

Implementing immediate skin-to-skin contact (SSC) after Cesarean section could significantly improve maternal physiological and psychological well-being, potentially reducing stress and enhancing bonding. If this pilot study's hypothesis is confirmed, it could lead to revised C-section protocols, prioritizing early SSC in the operating room. This would offer a more holistic postpartum experience, potentially boosting breastfeeding success and supporting maternal mental health from the earliest moments. The findings could inform clinical guidelines, making immediate SSC a standard practice, thereby optimizing the critical initial hours for both mother and infant.


Source: clinicaltrials:NCT01894880 · Ingested 2026-06-17 · Digest: gemini-2.5-flash