Plecanatide 3 mg dose offers optimal balance for chronic constipation and IBS-C, boosting bowel movements
Gut relief revisited: plecanatide in chronic idiopathic constipation and irritable bowel syndrome with constipation - a systematic review and meta-analysis with GRADE assessment.
Abstract
Plecanatide significantly increased complete spontaneous bowel movements (CSBMs) across all doses in chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C), with the 3 mg dose demonstrating the best efficacy-safety balance.