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2026-10-26 PubMed

Once-daily insulin regimens cut district nurse visits 77%, improved HbA1c 1.5% in T2DM.

Reducing diabetes care costs and district nurse visits through novel insulin regimens.

Background

Type 2 diabetes in an increasingly frail and aging population places unsustainable demand on district nursing teams for insulin administration. Current regimens often require frequent visits, straining resources and potentially increasing patient burden. Simplified insulin protocols are crucial to alleviate this pressure while maintaining or improving glycemic control and patient outcomes. This initiative addresses the gap by optimizing insulin delivery frequency.

Study Design

This quality improvement initiative targeted type 2 diabetes patients receiving district nurse visits for insulin administration. The integrated community care team audited eligible individuals, and community diabetes specialist nurses provided personalized guides to adjust insulin regimens from twice to once daily. The primary endpoints were reduction in nurse visits and changes in HbA1c levels, assessed over a 3-year follow-up period.

Results

Adjusting insulin regimens from twice to once daily led to a 77% reduction in twice-daily district nurse visits.

Mean HbA1c significantly decreased by 16.3 mmol/mol (1.5%) at 12 months, moving from a baseline of 94.9 mmol/mol (10.8%) to 78.6 mmol/mol (9.3%). The median follow-up for patients was 18 months, during which a mortality rate of 30% was observed. This indicates improved glycemic control alongside reduced healthcare burden.

Key Findings

  • District nurse visits for twice-daily insulin administration reduced by 77%.
  • Mean HbA1c significantly decreased by 1.5% (from 10.8% to 9.3%) at 12 months.
  • Estimated annual cost savings of approximately £839,500 were achieved.
  • Median patient follow-up was 18 months, with a 30% mortality rate.

Why It Matters

Simplifying insulin regimens to once daily can significantly reduce the workload on district nursing teams and improve patient outcomes. This approach offers a practical solution to the increasing demand for home healthcare, freeing up resources for other critical needs. The estimated annual savings of approximately £839,500 highlight the substantial economic benefit. For patients, this could mean less frequent interactions with nurses while maintaining or improving glycemic control, potentially enhancing independence and quality of life. This model is highly translatable for healthcare systems facing similar challenges.


insulin type 2 diabetes t2dm glycemic control healthcare costs nursing
Source: pubmed:42932244 · Ingested Oct 26, 2026 · Digest: gemini-2.5-flash