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Tirzepatide 2026-09-13 PubMed

GLP-1 Receptor Agonists Show No Bone Effect, Significantly Reduce Lean Body Mass in Meta-Analysis

GLP-1 Receptor Agonists and Musculoskeletal Outcomes: A Systematic Literature Review and Meta-Analysis.

Abstract

GLP-1 RAs showed no bone or fracture effect in a meta-analysis, but consistently reduced lean body mass by a standardized mean difference of 0.52.


Source: pubmed:42730869 · Ingested Sep 13, 2026 · Digest: gemini-2.5-flash