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2026-08-04 PubMed

IGFBP2 reprograms tumor microenvironment via IGF-independent integrin and nuclear pathways, driving therapy resistance.

Rewiring the tumor microenvironment: IGFBP2 at the Nexus of remodeling and therapy resistance?

Abstract

IGFBP2 reprograms the tumor microenvironment via IGF-independent integrin and nuclear pathways, driving therapy resistance and tumor aggressiveness.


Source: pubmed:42546854 · Ingested 2026-08-04 · Digest: gemini-2.5-flash