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2026-07-31 PubMed

[177Lu]Lu-PSMA-597 dose-intensification trial OPTIMAL-PSMA aims for superior PSA response in mCRPC.

A Phase 2, Open-Label, Randomized Controlled Trial Evaluating Safety and Efficacy of Dose-Intensified Versus Standard Dosing Regimens of [177Lu]Lu-PSMA-597 in mCRPC (OPTIMAL-PSMA).

Abstract

OPTIMAL-PSMA, a Phase 2 RCT, evaluates if dose-intensified [177Lu]Lu-PSMA-597 improves PSA response in mCRPC compared to standard dosing.


Source: pubmed:42532645 Β· Ingested 2026-07-31 Β· Digest: gemini-2.5-flash