AC02, a novel synthetic ACTH peptide, shows comparable pharmacodynamics to porcine ACTH1-39 for infantile spasms.
Pharmacokinetics, Pharmacodynamics and Immunogenicity of AC02, a Novel Synthetic Derivate Peptide of Human Adrenocorticotropic Hormone for Infantile Spasms.
Abstract
AC02, a synthetic ACTH derivative, demonstrated favorable pharmacokinetics and free cortisol responses comparable to porcine ACTH1-39 in a first-in-human study.