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2026-07-24 PubMed

Atogepant versus topiramate trial (TEMPLE) evaluated tolerability, safety, and efficacy in migraine prevention.

Tolerability, safety, and efficacy of atogepant versus topiramate in adults with migraine (TEMPLE): a randomised, head-to-head, phase 3b trial.

Abstract

The TEMPLE trial, a phase 3b study, aimed to compare atogepant 60 mg daily against topiramate for tolerability, safety, and efficacy in adults with migraine.


Source: pubmed:42492556 · Ingested 2026-07-24 · Digest: gemini-2.5-flash