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2026-07-09 PubMed

Polydatin halts hippocampal neurodegeneration in diabetic rats by suppressing oxidative stress and NF-κB/COX-2/IL-6 inflammation.

Polydatin inhibits hippocampal neurodegeneration in diabetic rats via modulation of oxidative stress and NF-kB/COX-2/IL-6 inflammatory pathway.

Abstract

Polydatin (PLD) significantly reduced hippocampal neurodegeneration in diabetic rats by lowering blood glucose, oxidative stress, and inflammation, suggesting multi-target protective effects.


Source: pubmed:42423809 · Ingested 2026-07-09 · Digest: gemini-2.5-flash