Parvovirus B19 infection presents as acute polyarthritis in 93% of patients, with 14% progressing to chronic inflammation
Parvovirus B19 infection presenting as polyarthritis: a nationwide clinical and epidemiological study.
Background
Viral arthritis accounts for approximately 1% of acute arthritis cases, with parvovirus B19 (B19V) being a particularly common etiology. Diagnosis typically involves clinical presentation and B19V seropositivity, alongside exclusion of other causes. While B19V DNA and antigens are frequently detected in synovial tissue, the precise mechanisms linking B19V infection to bone destruction and chronic inflammatory conditions remain unclear. This study aimed to characterize the clinical and laboratory manifestations of B19V-associated arthritis and assess its progression.