CD109 Drives Colorectal Cancer Stemness and Chemoresistance via LRRC8A/AKAP12/PKCα-Mediated STAT3 and WNT Signaling
CD109 Drives Stemness and Chemoresistance in Colorectal Cancer via LRRC8A/AKAP12/PKCα-Mediated STAT3 Activation and WNT Signaling.
Abstract
CD109 drives colorectal cancer stemness and chemoresistance by activating STAT3 and WNT signaling through the LRRC8A/AKAP12/PKCα axis, making it a potential therapeutic target.