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2026-06-16 PubMed

Ultrasound-activated CMB Gel reprograms mitochondrial epigenetics via `mTOR`/`GATD3A` to treat osteoarthritis

Ultrasound-Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis.

Abstract

Ultrasound-activated CMB Gel epigenetically reprogrammed chondrocytes via mTOR/GATD3A to clear damaged mitochondria, treating osteoarthritis in mice.


Source: pubmed:42301238 · Ingested 2026-06-16 · Digest: gemini-2.5-flash