Polydopamine-coated sponge with TRAP and antibacterial peptide targets hemostasis and infected wound healing.

Wound treatment faces significant challenges from persistent bleeding and infections, which complicate healing and increase morbidity. Current standard-of-care often struggles to simultaneously address both issues effectively, leading to prolonged recovery times and potential complications. The development of advanced biomaterials capable of rapid hemostasis and broad-spectrum antibacterial activity is crucial. This research addresses the critical need for integrated therapeutic solutions that can manage the complex and variable microenvironment of infected wounds, promoting faster tissue repair and preventing systemic complications.