Orally Active Growth Hormone Secretagogues: Current Status and Future Clinical Use

Growth hormone (GH) plays a crucial role in metabolism, body composition, and overall well-being, but its therapeutic administration has traditionally been limited to inconvenient injections. Growth hormone secretagogues (GHS) are a class of compounds designed to stimulate the body's natural production and release of GH, offering a potentially more patient-friendly approach. This comprehensive review addresses the current understanding of orally active GHS, their mechanisms, and their potential for clinical application, aiming to overcome the challenges associated with injectable GH therapy and explore new therapeutic avenues.