GDF-15/GFRAL axis integrates multiorgan-to-brain stress signals in bariatric surgery, influencing neuropsychiatric outcomes
GDF-15/GFRAL Axis Dynamics and Vulnerability Windows in Bariatric Surgery: Pathophysiological, Microbiomic, and Pharmacological Perspectives
Abstract
A review highlights the GDF-15/GFRAL axis as a critical neuroendocrine pathway integrating peripheral stress signals with central metabolic control, influencing neuropsychiatric adaptations post-bariatric surgery.