Topical Zinc/Taurine/Panthenol cream demonstrates skin acceptability in females with urinary incontinence

Urinary incontinence (UI) affects a significant portion of women, leading to substantial quality of life issues, including stigmatization, depression, and anxiety. A common complication is incontinence-associated dermatitis (IAD), characterized by inflamed, erythematous skin, often with erosion and secondary infection. IAD results from chronic exposure to urine/stool, an alkaline pH, and overhydration, compounded by friction from incontinence pads, which compromises skin barrier function. Current care often involves barrier creams, but novel formulations are sought to improve skin health and acceptability.

This study evaluated the skin acceptability of a topical cream containing zinc oxide, zinc gluconate, taurine, and panthenol in females experiencing urinary incontinence. The specific study design, participant number (n), dosing regimen (e.g., frequency, duration), and primary endpoints beyond general 'skin acceptability' are not detailed in the provided abstract/introduction. No control arm or specific assay methods (ELISA, qPCR) were mentioned in the available text.

The provided research record, consisting solely of the title and introduction, does not contain specific quantitative results regarding the skin acceptability of the topical cream. No percentages, p-values, fold-changes, or other statistical data are available to report from this excerpt. Therefore, no specific findings can be extracted from the provided text to meet the detailed reporting requirements for this section.