Yili child formula milk and regular milk trial to assess bone health and growth in 4-6 year olds
Background
Adequate nutrition is critical for optimal bone health and growth during early childhood, a period of rapid development. Dairy products, particularly milk, are well-established sources of calcium and vitamin D, essential nutrients for bone mineralization. However, the comparative effects of specialized child formula milk versus regular milk, or a control diet, on specific bone health markers and growth parameters in young children remain an area of active investigation. This study aims to clarify these differential impacts, addressing a key nutritional gap.
Study Design
This cluster randomized controlled trial will enroll >=246 healthy children aged 4-6 years old from kindergartens in Hui-ning County, China. Participants are assigned to one of three arms for 12 months: Yili child formula milk (QQ star formula, SCI-PRO NUTR5+6TM) at *195 ml 2 /day, Yili regular milk (pure milk) at 195ml*2 /day, or a control group receiving ~50g/d grain foods. Primary endpoints include bone density and bone mineral content at the forearm and heel, and bone biomarkers, measured at 0, 6, and 12 months.
Why It Matters
This 12-month trial could provide crucial evidence for dietary recommendations concerning bone health in young children. If significant differences emerge, it could inform parents and pediatricians on the optimal choice between specialized formula milk and regular milk, or highlight the importance of adequate dairy intake versus other food groups. The findings may influence public health guidelines on childhood nutrition, potentially leading to revised dietary advice for promoting robust skeletal development. Understanding the comparative benefits of different milk types could refine nutritional strategies for long-term bone health.
milk
bone-health
children
randomized-controlled-trial
nutrition
growth