Multicenter study aims to establish diagnostic parameters for Relative Energy Deficiency in Sport (RED-S)

Relative Energy Deficiency in Sport (RED-S) is a critical concern for high-performance athletes, encompassing a spectrum of negative health and performance consequences stemming from chronic low energy availability. This syndrome affects junior and senior athletes globally, with prevalence rates estimated between 3-60%. Despite its widespread impact, current methods for assessing and diagnosing RED-S remain inadequate, leading to delayed recognition and suboptimal management. This diagnostic gap hinders effective intervention, potentially compromising athlete health, career longevity, and competitive performance, particularly in the lead-up to major events like the Olympic Games.

This multicenter study, registered as NCT05259969, aims to establish robust diagnostic and management parameters for RED-S. Researchers will screen a group of 25 competitive athletes recognized by the Olympic Committee of Slovenia. The screening involves a combination of validated and semi-validated questionnaires designed to identify low energy availability, RED-S, and eating disorder risk. The study protocol ensures subjects are fully informed about the procedure and aims, with the right to withdraw at any time, and will sign informed consent prior to participation.