Prospective 5-year observational study launched to track clinical and lab outcomes in obese patients undergoing lifestyle, medical, and surgical management.

The global prevalence of obesity continues to rise, with a significant increase in severe forms like stage III obesity, particularly in North America. This chronic condition is associated with numerous severe complications and has a major impact on quality of life. Current management strategies for obesity include lifestyle modifications, medical therapies, and surgical interventions like bariatric surgery. However, the long-term efficacy and comparative outcomes of these diverse approaches, especially when combined, require extensive real-world data. Understanding the natural history and progression of obesity, particularly in patients managed within a clinical setting, is crucial for optimizing treatment protocols and improving patient outcomes.

This is an observational study describing the design for tracking obese patients receiving various management strategies. Participants from the endocrinology clinic of Marmara University Medical School Hospital will be followed prospectively for 5 years. The study aims to monitor clinical and laboratory parameters over this duration to assess the long-term effects of lifestyle modification, medical, and surgical management.

This abstract describes the design of a prospective observational study and does not present any findings or results. Data collection is planned over a 5-year period to gather information on clinical and laboratory parameters in obese patients. The study's objective is to observe the natural course and outcomes of various obesity management approaches rather than to report immediate intervention results.