Dual Task Training Study to Analyze Balance, Gait, Cognition, Neurotrophic Factors in Parkinson's Disease

Parkinson's disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms like tremor, rigidity, and bradykinesia, but also significant non-motor symptoms including cognitive impairment and gait instability. These symptoms severely impact quality of life and increase fall risk. Current pharmacological treatments primarily target motor symptoms by replenishing dopamine, but often have limited efficacy on balance, gait, and cognitive deficits, and do not address underlying neurotrophic support. Investigating non-pharmacological interventions like dual task training is crucial to address these multifaceted challenges and potentially modulate neuroplasticity.

This study aims to investigate the effects of dual task training, a behavioral intervention combining motor and cognitive tasks, on key outcomes in Parkinson's disease patients. While specific details regarding the study design, such as participant n, intervention duration, frequency, or control group, are not provided in the abstract, the primary endpoints are clearly defined. Researchers plan to assess improvements in balance, gait, and cognition, alongside changes in neurotrophic factors, which are critical for neuronal survival and function.