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Semaglutide 2018-08-24 ClinicalTrials

Semaglutide effectiveness in real-world Type 2 Diabetes patients studied in Denmark and Sweden

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Denmark and Sweden, as Part of Local Clinical Practice (SURE DENMARK/SWEDEN)

Background

Type 2 Diabetes (T2D) is a chronic metabolic condition requiring effective long-term management to prevent complications. While clinical trials establish efficacy under controlled conditions, real-world data is crucial to understand how treatments perform in diverse patient populations and routine clinical practice. Semaglutide, a GLP-1R agonist, has demonstrated significant benefits in T2D management, but its effectiveness and patient experience in local clinical settings across different regions warrant further investigation. This study aims to bridge that gap by observing its use in Denmark and Sweden.

Study Design

This was a multi-center, prospective, non-interventional observational study conducted in Denmark and Sweden. Participants with Type 2 Diabetes receiving semaglutide as part of their routine clinical care were enrolled. The study aimed to collect real-world data on semaglutide effectiveness and patient experience over a 6 to 8 month period. Patients completed health and diabetes treatment questionnaires during their normally scheduled clinic visits. No specific dose or route was mandated beyond "semaglutide prescribed by the study doctor"; there was no control arm.

Why It Matters

Real-world evidence is vital for understanding how semaglutide performs outside of controlled clinical trials, informing prescribing practices and patient expectations. This study, though observational, contributes to a broader understanding of semaglutide's effectiveness and tolerability in diverse patient populations under routine care. For clinicians, such data can validate trial findings and highlight practical considerations for patient management. For individuals using or considering semaglutide, these insights help contextualize its benefits and potential challenges in everyday use, moving beyond idealized trial scenarios to reflect actual patient experiences.


semaglutide type-2-diabetes real-world-evidence observational-study glp-1-agonist denmark
Source: clinicaltrials:NCT03648281 · Ingested 2026-07-09 · Digest: gemini-2.5-flash