Liraglutide Explored for Cognitive Dysfunction in Mood Disorders
Background
Bipolar Disorder and Major Depressive Disorder are often accompanied by significant cognitive dysfunction, impacting daily life and treatment outcomes. While glucagon-like peptide-1 (GLP-1) agonists like liraglutide are primarily known for treating type 2 diabetes and obesity, emerging evidence suggests they may have neuroprotective and cognitive-enhancing effects. This Phase 3 clinical trial aimed to investigate the potential cognitive benefits of adjunctive liraglutide in patients with mood disorders.