Efficacy of Whey Protein, EAAs, and Vitamin D Supplementation Tested in Sarcopenic Elderly

Sarcopenia, the age-related loss of muscle mass and function, significantly impairs quality of life and increases morbidity in the elderly. Current interventions often fall short in fully reversing or preventing its progression, leading to increased frailty, falls, and healthcare burden. Nutritional support, particularly protein and vitamin D, combined with physical activity, represents a promising multi-modal strategy to counteract muscle wasting and associated inflammation, addressing a critical gap in comprehensive sarcopenia management.

This 3-month randomized, double-blind, placebo-controlled trial enrolled sarcopenic elderly participants. The intervention group received nutritional supplementation with whey protein, essential amino acids, and vitamin D concurrent with regular, controlled physical activity. The control group received a placebo. Primary endpoints included changes in muscle mass, strength, physical function, quality of life, and reductions in malnutrition risk and inflammation markers. The study aimed to test the hypothesis that this combined intervention would yield significant improvements across these measures.

This abstract describes the study design and hypothesis but does not present any results or findings from the trial. Therefore, no specific data, statistical outcomes, or quantitative changes in muscle mass, strength, physical function, quality of life, malnutrition risk, or inflammation markers can be reported from this source. The study's aim was to test the efficacy of the combined nutritional and physical activity intervention in sarcopenic elderly.