Thymic Secretions PTMα and Tβ15b1 Drive Breast Cancer Growth and Spread
Thymic function affects breast cancer development and metastasis by regulating expression of thymus secretions PTMα and Tβ15b1.
Background
Breast cancer remains a leading cause of cancer-related mortality worldwide, often due to its aggressive metastatic potential. The thymus, a vital organ for immune development, secretes various peptides that can influence cellular processes and overall health. While the general role of the immune system in cancer is well-established, the specific impact of individual thymic secretions like prothymosin alpha (PTMα) and thymosin beta 15b1 (Tβ15b1) on breast cancer progression and metastasis has remained largely unexplored.