GLP-1 Medicines: A Comprehensive Review of Efficacy and Safety for Metabolic Health
Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity.
Background
Type 2 Diabetes and Obesity represent global health epidemics, significantly increasing the risk of cardiovascular disease, kidney failure, and other severe comorbidities, placing immense strain on healthcare systems worldwide. Traditional therapeutic approaches often struggle to achieve sustained weight loss and optimal glycemic control, highlighting an urgent need for more effective and safer strategies. This pivotal review aims to comprehensively synthesize and critically evaluate the current understanding of GLP-1 receptor agonists' (GLP-1 RAs) efficacy and safety profiles across their various established and emerging clinical applications for managing both Type 2 Diabetes and Obesity.