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oxytocin other other 2022-03-01 ClinicalTrials

Stress Response Study Explores Oxytocin and Cortisol in Borderline Personality Disorder

Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder

Background

Individuals with Borderline Personality Disorder (BPD) often experience severe emotional dysregulation and altered stress responses. This complex mental health condition is characterized by impulsivity and unstable relationships, frequently involving dysregulation of key neurohormones. Specifically, oxytocin (a hormone crucial for social bonding and stress reduction) and cortisol (the body's primary stress hormone) are thought to play significant roles. While an interplay between these hormones is suspected, the precise dynamics of oxytocin and cortisol during acute psychosocial stress in young adult females with BPD remain largely unexplored.

Study Design

Population
Young adult females with Borderline Personality Disorder (BPD) experiencing acute psychosocial stress.
Intervention
Not specified; the study explores the dynamics of endogenous oxytocin and cortisol.
Outcome
The precise dynamics and interplay of oxytocin and cortisol during acute psychosocial stress.

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Source: clinicaltrials:NCT05357521 · Ingested 2026-04-24 · Digest: gemini-2.5-flash