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MGF 2017-03-24 ClinicalTrials

Milk or Soy Milk with Resistance Exercise Explored for Sarcopenia Management in Elderly

Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.

Background

Age-associated sarcopenia, characterized by progressive and generalized loss of skeletal muscle mass and strength, significantly impacts the quality of life and increases morbidity in older adults. This condition is often linked to complex physiological changes, including altered hormonal balance, chronic low-grade inflammation, and disrupted protein metabolism. Current standard-of-care often involves resistance exercise, but nutritional strategies, particularly protein supplementation, are crucial to counteract muscle atrophy, where myokines and cytokines play central roles. There remains a need for accessible, effective, and integrated nutritional interventions to augment the benefits of exercise in managing sarcopenia.

Study Design

This randomized controlled trial recruited elderly people ≧65 years old with sarcopenia from nursing homes in Taipei, Taiwan, between June and December 2017. Participants were assigned to three groups: a control group, a milk supplement group, and a soy milk supplement group. The milk and soy milk groups received 200 mL milk or soy milk two times per day. All participants engaged in a structured resistance exercise training program, conducted three times per week for 30 minutes per session. After a 12-week intervention period, researchers measured anthropometry, sarcopenia index, blood biochemical markers, nutrition status index, inflammation index, insulin resistance index, and dietary intake using various assays like ELISA and blood chemistry panels.

Results

The provided abstract for this study does not contain specific quantitative results regarding the impact of milk or soy milk supplementation combined with resistance exercise on sarcopenia indices, anthropometry, blood biochemical markers, nutritional status, inflammation, or insulin resistance after the 12-week intervention period. Therefore, no specific findings, statistical outcomes, or p-values can be reported from the provided text. The abstract outlines the study's design and methods but omits the data analysis and conclusions, preventing a detailed summary of what they found.

Why It Matters

While specific results are not available in the abstract, this study design explores a highly relevant and practical approach to combating sarcopenia in vulnerable populations. Integrating readily available and affordable nutritional supplements like milk or soy milk with resistance exercise could offer a scalable strategy for elderly care. If positive outcomes were found, such a protocol could significantly enhance muscle mass, strength, and overall functional independence, potentially reducing falls and improving quality of life in nursing home residents. This research highlights the importance of multi-modal interventions that combine both dietary and physical activity components to effectively manage age-related muscle decline, offering a blueprint for future studies to validate and implement in clinical settings.


sarcopenia elderly resistance-exercise milk soy-milk nutrition-supplementation
Source: clinicaltrials:NCT05035121 · Ingested 2026-05-29 · Digest: gemini-2.5-flash